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Material Safety Data Sheet
Sodium Fluoride, 97%
ACC# 96497 Section 1 - Chemical Product and Company Identification
MSDS Name: Sodium Fluoride, 97%
Catalog Numbers: AC191270000, AC191270010, AC191270250, AC191275000
Synonyms: Disodium difluoride; Fluoride, sodium; Sodium fluoride cyclic dimer;
Sodium hydrofluoride; Sodium monofluoride;
Trisodium trifluoride
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
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800-ACROS-01
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For emergencies in the US, call CHEMTREC:
800-424-9300
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800-424-9300
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Section 2 - Composition, Information on Ingredients
CAS#Chemical NamePercentEINECS/ELINCS
7681-49-4Sodium fluoride97 231-667-8
Hazard Symbols: T
Risk Phrases: 25 32 36/38
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: white to off-white crystalline powder. Danger! Causes digestive
and
respiratory tract burns. Harmful if swallowed. May cause severe respiratory
tract irritation with possible burns.
May cause severe digestive tract
irritation with possible burns. Moisture sensitive. This substance has caused
adverse
reproductive and fetal effects in animals. May cause lung damage. Causes
eye and skin irritation and possible burns.
Target
Organs: Kidneys, heart, gastrointestinal system, skeletal structures,
teeth, nerves, bone.
Potential Health Effects
Eye: Causes eye irritation and possible burns. May cause chemical
conjunctivitis
and corneal damage.
Skin: Contact with skin causes irritation and possible burns, especially if the
skin is wet or moist. May cause skin rash (in milder cases), and cold and clammy
skin with cyanosis or pale color.
Ingestion: Ingestion of large amounts of fluoride may cause salivation, nausea,
vomiting, abdominal pain, fever, labored
breathing. Exposure to fluoride
compounds can result in systemic toxic effects on the heart, liver, and kidneys.
It
may also deplete calcium levels in the body leading to hypocalcemia and
death. May cause irritation of the digestive tract
and possible burns. May cause
respiratory paralysis and cardiac arrest.
Inhalation: May cause severe irritation of
the respiratory tract with possible
burns. Aspiration may lead to pulmonary edema. Prolonged exposure to dusts,
vapors,
or mists may result in the perforation of the nasal septum. May cause
systemic effects.
Chronic: Chronic inhalation
and ingestion may cause chronic fluoride poisoning
(fluorosis) characterized by weight loss, weakness, anemia, brittle
bones, and
stiff joints. May cause reproductive and fetal effects. Effects may be delayed.
Chronic exposure may cause
lung damage. Laboratory experiments have resulted in
mutagenic effects. Chronic exposure to fluoride compounds may cause
systemic
toxicity. Skeletal effects may include bone brittleness, joint stiffness, teeth
discoloration, tendon calcification,
and osterosclerosis. Animal studies have
reported the development of tumors.
Section
4 - First Aid Measures
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes
closed. Extensive
irrigation with water is required (at least 30 minutes).
Skin: Get medical aid immediately. Immediately flush skin with
plenty of water
for at least 15 minutes while removing contaminated clothing and shoes. Wash
clothing before reuse.
Destroy contaminated shoes.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls
of milk or water. Never give anything by mouth to an unconscious person.
Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen.
Do NOT use
mouth-to-mouth resuscitation. If breathing has ceased apply artificial
respiration using oxygen and a suitable
mechanical device such as a bag and a
mask.
Notes to Physician: Individuals who suffer from diabetes insipidus or
some form
of renal impairment may be at increased risk from the effects of fluoride. Due
to delayed and persistent
symptoms, observe patient closely for 48 hours. Treat
symptomatically and supportively.
Antidote: None reported.
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus
in pressure-demand,
MSHA/NIOSH (approved or equivalent), and full protective
gear. Material will not burn. During a fire, irritating and highly
toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media: Use extinguishing media
most appropriate for the
surrounding fire. Do NOT get water inside containers. Use water spray, dry
chemical, carbon
dioxide, or appropriate foam.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits,
Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in
Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal
container. Do not flush into a sewer.
Clean up spills immediately, observing
precautions in the Protective Equipment section. Avoid generating dusty
conditions.
Provide ventilation. Do not get water inside containers.
Section 7 - Handling and Storage
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash
before reuse.
Use only in a well-ventilated area. Minimize dust generation and
accumulation. Do not get in eyes, on skin, or on clothing.
Keep container
tightly closed. Do not ingest or inhale. Do not allow contact with water.
Discard contaminated shoes.
Keep from contact with moist air and steam.
Storage: Keep container closed when not in use. Store in a tightly closed
container. Store in a cool, dry, well-ventilated area away from incompatible
substances. Keep away from strong acids.
Store protected from moisture. Store
away from alkalies.
Section 8 - Exposure Controls,
Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be
equipped with
an eyewash facility and a safety shower. Use adequate ventilation
to keep airborne concentrations low.
Exposure Limits
Chemical NameACGIHNIOSHOSHA - Final PELs
Sodium fluoridenone listed2.5 mg/m3 TWA (as F)none
listed
OSHA Vacated PELs: Sodium fluoride: No OSHA Vacated PELs are listed for this
chemical.
Personal
Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as
described by OSHA's
eye and face protection regulations in 29 CFR 1910.133 or
European Standard EN166.
Skin: Wear appropriate protective
gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134
and ANSI Z88.2 requirements or European Standard EN
149 must be followed
whenever workplace conditions warrant a respirator's use.
Section
9 - Physical and Chemical Properties
Physical State: Crystalline powder
Appearance: white to off-white
Odor: odorless
pH:
7.4 (solution)
Vapor Pressure: 1 mm Hg @ 1077 deg C
Vapor Density: 1.45 (air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 1704 deg C
Freezing/Melting Point:993 deg C
Decomposition Temperature:Not
available.
Solubility: Soluble.
Specific Gravity/Density:2.78 (water=1)
Molecular Formula:NaF
Molecular Weight:41.9882
Section 10 - Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures. Moisture
sensitive.
Conditions
to Avoid: Incompatible materials, dust generation, moisture, excess
heat.
Incompatibilities with Other Materials:
Moisture, acids, alkalies, glass,
oxidizing agents.
Hazardous Decomposition Products: Irritating and toxic fumes and
gases, hydrogen
fluoride gas, sodium oxide.
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
RTECS#:
CAS# 7681-49-4: WB0350000
LD50/LC50:
CAS# 7681-49-4:
Draize test, rabbit,
eye: 20 mg/24H Moderate;
Oral, mouse: LD50 = 44 mg/kg;
Oral, rabbit: LD50 = 200 mg/kg;
Oral, rat: LD50 = 31 mg/kg;
Carcinogenicity:
CAS# 7681-49-4: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: Oral, rat: TDLo
= 617 mg/kg/2Y-C (Tumorigenic - equivocal tu
morigenic agent by RTECS criteria - Endocrine - thyroid tumo rsand
Musculoskeletal
- tumors.; Oral, mouse: TDLo = 14 mg/kg/43W-C (Tumorigenic -
equivocal tumor igenic agent by RTECS criteria - Skin and
Appendages - tum ors.
Teratogenicity: Oral, rat: TDLo = 240 mg/kg (female 11-14 day(s) after
conception) Specific
Developmental Abnormalities - musculoskeletal system.;
Oral, rat: TDLo = 255 mg/kg (female 85 day(s) pre-mating) Specific
Developmental
Abnormalities - Central Nervous System.; Intraperitoneal, rat: TDLo = 9 mg/kg
(female 10-18 day(s) after
conception) Effects on Embryo or Fetus -
extra-embryonic structures (e.g., placenta, umbilical cord) and Effects on
Embryo
or Fetus - fetal death.
Reproductive Effects: Oral, rat: TDLo = 150 mg/kg (male 30 day(s) pre-mating)
Reproductive
- Paternal Effects - spermatogenesis (incl. genetic material, sperm
morphology, motility, and count) and Paternal Effects
- testes, epididymis,
sperm duct and Fertility - male fertility index (e.g. # males impregnating
females per # males
exposed to fertile nonpregnant females).; Oral, rat: TDLo =
221 mg/kg (female 1-20 day(s) after conception) Fertility
- post-implantation
mortality (e.g. dead and/or resorbed implants per total number of implants).
Neurotoxicity: No
information available.
Mutagenicity: DNA Inhibition: Human, Fibroblast = 100 mg/L.; Cytogenetic
Analysis: Human, Fibroblast
= 20 mg/L.; Cytogenetic Analysis: Human, Lymphocyte
= 20 mg/L.; Mutation in Mammalian Somatic Cells: Human, Lymphocyte
= 440 mg/L.
Other Studies: Standard Draize Test: Administration into the eye (rabbit) = 20
mg/24H (Moderate).
Section 12 - Ecological Information
Ecotoxicity: Fish: Mosquito Fish: TLm = 419 ppm; 96 Hr; Fresh waterWater flea
Daphnia: LC50
= 340 mg/L; 48 Hr; Unspecified No data available.
Environmental: Toxic to aquatic and plant life. Soil can bind fluorides
tightly
if the pH is greater than 6.5. Fluorides can be damaging to plants when present
in acid soils.
Physical:
No information available.
Other: Dangerous to aquatic life in high concentrations.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is
classified as a hazardous
waste. US EPA guidelines for the classification
determination are listed in 40 CFR Parts 261.3. Additionally, waste generators
must consult state and local hazardous waste regulations to ensure complete and
accurate classification.
RCRA
P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
US DOTIATARID/ADRIMOCanada TDG
Shipping
Name:SODIUM FLUORIDENo information available.
Hazard Class:6.1
UN Number:UN1690
Packing Group:III
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 7681-49-4 is listed on the TSCA inventory.
Health & Safety Reporting List
None
of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product
are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant
New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
CAS# 7681-49-4: 1000 lb final RQ; 454 kg final
RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS
# 7681-49-4: acute, chronic.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This
material does not contain any hazardous air pollutants. This material does
not contain any Class 1 Ozone depletors. This
material does not contain any
Class 2 Ozone depletors.
Clean Water Act:
CAS# 7681-49-4 is listed as a Hazardous
Substance under the CWA. None of the
chemicals in this product are listed as Priority Pollutants under the CWA. None
of
the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 7681-49-4 can be found on the following state right to know lists:
California, New Jersey, Pennsylvania, Massachusetts.
California No Significant Risk Level: None of the chemicals in
this product are
listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard
Symbols:
T
Risk Phrases:
R 25 Toxic if swallowed.
R 32 Contact with acids liberates very toxic gas.
R 36/38
Irritating to eyes and skin.
Safety Phrases:
S 22 Do not breathe dust.
S 36 Wear suitable protective clothing.
S 45
In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 7681-49-4: 1
Canada - DSL/NDSL
CAS# 7681-49-4 is listed
on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D1B, D2A, D2B.
Canadian Ingredient
Disclosure List
CAS# 7681-49-4 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 7681-49-4:
OEL-AUSTRALIA:TWA 2.5 mg(F)/m3 OEL-BELGIUM:TWA 2.5
mg(F)/m3 OEL-CZECHOSLOVAKIA:TWA 1 mg(F)/m3;STEL 5 mg(F)/m3 OEL-DENMA
RK:TWA
2.5 mg(F)/m3 OEL-FINLAND:TWA 2.5 mg(F)/m3 OEL-FRANCE:TWA 2 mg
/m3 OEL-FRANCE:TWA 2.5 mg(F)/m3 OEL-GERMANY:TWA 2.5 mg(F)/m3
OEL-HU
NGARY:TWA 1 mg(F)/m3;STEL 2 mg(F)/m3 OEL-THE NETHERLANDS:TWA 2.5 mg(F
)/m3 OEL-THE PHILIPPINES:TWA 2.5 mg(F)/m3
OEL-POLAND:TWA 1 mg(F)/m3
OEL-RUSSIA:TWA 0.2 mg/m3;STEL 1 mg/m3 OEL-SWEDEN:TWA 2 mg(F)/m3 OEL
-SWITZERLAND:TWA 1.8
ppm (1.5 mg(F)/m3);STEL 9.0 ppm OEL-THAILAND:TWA
2.5 mg(F)/m3 OEL-TURKEY:TWA 2.5 mg(F)/m3 OEL-UNITED KINGDOM:TWA 2.5
mg(F)/m3
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV O
EL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 - Additional Information
MSDS Creation Date: 7/07/1999
Revision #3 Date: 3/04/2004
The information above is believed to be accurate and represents the best
information currently
available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect
to such
information, and we assume no liability resulting from its use. Users should
make their own investigations
to determine the suitability of the information
for their particular purposes. In no event shall Fisher be liable for
any
claims, losses, or damages of any third party or for lost profits or any
special, indirect, incidental, consequential
or exemplary damages, howsoever
arising, even if Fisher has been advised of the possibility of such damages.
